Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein.
The proteins S100A9 and S100A12 are associated with the human S100 calcium-binding protein family.These proteins promote interaction with target proteins and alter their conformation when they bind to calcium ions bml basic in EF-hand motifs.The V domain of RAGE (Receptor for Advanced Glycation End products) is crucial for S100A9 binding.The bindin